Both TOBI and Cayston are inhaled antibiotics that are used to treat CF patients who are infected with pseudomonas aeruginosa. Cayston is the newer antibiotic that hit the market back in 2010, and even more recently there was a new form of TOBI released that comes in a podhaler which older CF patients can use instead of nebulizing TOBI.
Some patients who are colonized with pseudomonas or have recurring infections might alternate between TOBI and Cayston to try to eradicate the infections, or may do a plan with just TOBI that could be 1 month on TOBI and 1 month off TOBI, repeating it as necessary. Like so many other aspects of this disease, that will vary on the individual and the course of action their CF team recommends.
We experienced our first 28 day cycle of TOBI when Judith was 16 months old and she had her first positive pseudomonas culture. The nebulized treatment took us about 20-25 minutes to complete, twice a day. You need to do treatments with inhaled antibiotics after airway clearance therapies, because you don’t want them to be coughed out of the lungs. The whole point is to get them to stay in there and fight the bacteria, so it is crucial to do this as one of the last parts of your treatment time block.
Sources: http://www.cff.org/treatments/Therapies/Respiratory/TOBI/#
http://www.cff.org/treatments/Therapies/Respiratory/Cayston/
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